The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2015

Filed:

Mar. 04, 2013
Applicant:

Ajinomoto Co., Inc., Tokyo, JP;

Inventor:

Gen Nonaka, Kanagawa, JP;

Assignee:

Ajinomoto Co., Inc., Tokyo, JP;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 13/12 (2006.01); C12P 17/16 (2006.01); C12N 1/21 (2006.01); C07K 14/245 (2006.01); C12N 9/10 (2006.01); C12N 9/04 (2006.01); C12R 1/19 (2006.01);
U.S. Cl.
CPC ...
C12P 13/12 (2013.01); C12P 17/16 (2013.01); C07K 14/245 (2013.01); C12N 9/1029 (2013.01); C12N 9/0006 (2013.01); C12R 1/19 (2013.01);
Abstract

A novel technique for improving the production by bacteria of amino acids that contain sulfur has been developed, and thereby a sulfur-containing amino acid-producing bacterium, and a method for producing a compound such as a sulfur-containing amino acid are provided. A sulfur-containing amino acid, a related substance thereof, or a mixture of these can be produced by culturing a bacterium belonging to the family Enterobacteriaceae, which has a sulfur-containing amino acid-producing ability and has been modified so that the activity of the protein encoded by the yeeE gene, for example, the protein of the following (A) or (B), is increased in a medium, and collecting a sulfur-containing amino acid, a related substance thereof, or a mixture of them from the medium: (A) a protein having the amino acid sequence of SEQ ID NO: 14, (B) a protein having the amino acid sequence of SEQ ID NO: 14 but which includes one or several amino acid substitutions, deletions, insertions, or additions, and when the intracellular activity of this protein is increased, the ability of the bacterium to produce a sulfur-containing amino acid is improved.


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