The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2015

Filed:

Apr. 12, 2010
Applicants:

Richard DE Wijn, Nijmegen, NL;

Robby Ruijtenbeek, Utrecht, NL;

Maria Helena Hilhorst, Wageningen, NL;

Michael Maria Van Den Heuvel, Amsterdam, NL;

Houke Marian Klomp, Amsterdam, NL;

Inventors:

Richard De Wijn, Nijmegen, NL;

Robby Ruijtenbeek, Utrecht, NL;

Maria Helena Hilhorst, Wageningen, NL;

Michael Maria Van Den Heuvel, Amsterdam, NL;

Houke Marian Klomp, Amsterdam, NL;

Assignees:

Pamgene B.V., 's-Hertogenbosch, NL;

Stichting Het Nederlands Kanker Instituut, Amsterdam, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/00 (2006.01); C12Q 1/48 (2006.01); G01N 33/48 (2006.01); C40B 30/08 (2006.01); C40B 30/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a method for determining or predicting the response of a patient diagnosed with non small cell lung cancer to targeted pharmacotherapy. The present invention also aims to provide methods and devices for predicting the response of patients diagnosed with non small cell lung cancer to specific medicaments. More specifically, the present invention provides methods which measure kinase activity by studying phosphorylation levels and profiles and inhibitions thereof by drugs in samples of said patients.


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