The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2015
Filed:
Mar. 12, 2013
Applicant:
The Chinese University of Hong Kong, Shatin, New Territories, CN;
Inventors:
Jun Yu, Lake Silver, CN;
Joseph Jao Yiu Sung, Man On san, CN;
Assignee:
The Chinese University of Hong Kong, Shatin, N.T., HK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); C12Q 1/68 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 14/435 (2013.01); C12Q 1/6886 (2013.01); G01N 33/6893 (2013.01);
Abstract
The present invention provides a method for diagnosing and determining prognosis of gastric cancer in a subject by detecting suppressed expression of the ADAMTS9 gene, which in some cases is due to elevated methylation level in the genomic sequence of this gene. A kit and device useful for such a method are also provided. In addition, the present invention provides a method for treating gastric cancer by increasing ADAMTS9 gene expression or activity.