The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2015
Filed:
Dec. 01, 2010
Alan R. Davis, Missouri City, TX (US);
Elizabeth A. Davis, Missouri City, TX (US);
Kevin Moran, The Woodlands, TX (US);
Ronke Olabisi, Houston, TX (US);
Jennifer L. West, Houston, TX (US);
Christy Franco, Houston, TX (US);
Alan R. Davis, Missouri City, TX (US);
Elizabeth A. Davis, Missouri City, TX (US);
Kevin Moran, The Woodlands, TX (US);
Ronke Olabisi, Houston, TX (US);
Jennifer L. West, Houston, TX (US);
Christy Franco, Houston, TX (US);
Baylor College of Medicine, Houston, TX (US);
William Marsh Rice University, Houston, TX (US);
Abstract
A method and system to induce bone growth by locally delivering bone morphogenetic proteins (BMPs) to the target location for a prolonged period without invasive procedures are disclosed. The new bone growth is induced by delivering cells producing BMPs from transduced viral vectors to the target cite. In various embodiments, the cells are encapsulated in hydrogel microspheres that are non-degradable or degradable by enzymes produced during the bone formation process. Various embodiments may be used to induce spinal fusion or repair critical bone defects.