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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8961986 B1

PDFFull Text
Date of Patent:
Feb. 24, 2015

Filed:

Dec. 06, 2012

Peptide composition

Applicant:

Apitope Technology (Bristol) Limited, Bristol, GB;

Inventors:

David Wraith, Bristol, GB;

Heather Barbara Streeter, Bristol, GB;

Assignee:

Apitope Technology (Bristol) Limited, Bristol, GB;

Attorney:

Marshall, Gerstein & Borun LLP

Primary Examiner:

Nora Rooney

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/04 (2006.01); A61K 39/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); C07K 14/47 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0008 (2013.01); C07K 14/4713 (2013.01); G01N 33/505 (2013.01);
Abstract

There is provided a method for selecting a tolerogenic peptide by selecting a peptide which is capable of binding to an MHC class I or II molecule without further processing. There is also provided a peptide selected by such a method and its use in a pharmaceutical composition and a method to treat and/or prevent a disease. The present invention also relates to a composition which comprises the following myelin basic protein peptides: MBP 30-44; MBP 83-99; MBP 131-145; and MBP 140-154. The composition may be used to treat a disease, in particular multiple sclerosis and/or optical neuritis and the invention also relates to such uses and methods.

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