The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2015

Filed:

Oct. 07, 2010
Applicants:

Randall T. Irvin, Sherwood Park, CA;

Elisabeth M. Davis, Edmonton, CA;

Dongyang LI, Edmonton, CA;

Inventors:

Randall T. Irvin, Sherwood Park, CA;

Elisabeth M. Davis, Edmonton, CA;

DongYang Li, Edmonton, CA;

Assignee:

Arch Biophysics, Inc., Alberta, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/108 (2006.01); A61K 39/02 (2006.01); C07K 14/21 (2006.01); A61B 5/145 (2006.01); A61L 27/04 (2006.01); A61L 27/34 (2006.01); A61L 27/54 (2006.01); A61L 31/02 (2006.01); A61L 31/04 (2006.01); A61L 31/10 (2006.01); A61L 31/16 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C07K 14/21 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61L 27/04 (2013.01); A61L 27/34 (2013.01); A61L 27/54 (2013.01); A61L 31/022 (2013.01); A61L 31/047 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01); C12N 15/1037 (2013.01); A61L 2400/18 (2013.01);
Abstract

The present invention relates to a method for covalently attaching a compound to a stainless steel, tin, iron, or titanium substrate, by contacting exposed surface(s) of the substrate with a synthetic pilin peptide containing a disulfide loop derived from the C-terminal receptor binding protein of Type IV(T4P) pilin, to bind the pilin peptide to the exposed surface(s), and covalently attaching the compound to the pilin peptide. Also disclosed are a substrate formed by the method and a biosensor device that uses the uses. Also disclosed are methods for improving the corrosion resistance, adhesive force, hardness and electron work function of certain metals.


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