The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2015
Filed:
Sep. 05, 2014
Applicant:
National University Corporation Tokyo Medical and Dental University, Tokyo, JP;
Inventors:
Kazunari Akiyoshi, Tokyo, JP;
Hiroshi Kiyono, Tokyo, JP;
Yoshikazu Yuki, Tokyo, JP;
Tomonori Nochi, Chapel Hill, NC (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 39/12 (2006.01); A61K 39/385 (2006.01); A61K 47/00 (2006.01); A61K 39/08 (2006.01);
U.S. Cl.
CPC ...
A61K 39/08 (2013.01); A61K 2039/541 (2013.01); A61K 2039/6087 (2013.01);
Abstract
A mucosal vaccine for the prevention or treatment of microbial infections is described that is capable of inducing vaccine antigen-specific immune responses in an organism without the addition of a mucosal adjuvant. The mucosal vaccine comprises a composite of a nanogel comprising a hydrophilic polysaccharide having a cationic functional group and a hydrophobic cholesterol added thereto as a side chain and a vaccine antigen. The vaccine is administered via a mucosal route.