The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2015

Filed:

Mar. 13, 2013
Applicants:

Xizhong Huang, Southborough, MA (US);

Malte Peters, Basel, CH;

Jennifer Lorraine Gansert, Simi Valley, CA (US);

David Dong Eun Chang, Calabasas, CA (US);

Pedro Beltran, Thousand Oaks, CA (US);

Zhu Alexander Cao, Acton, MA (US);

Inventors:

Xizhong Huang, Southborough, MA (US);

Malte Peters, Basel, CH;

Jennifer Lorraine Gansert, Simi Valley, CA (US);

David Dong Eun Chang, Calabasas, CA (US);

Pedro Beltran, Thousand Oaks, CA (US);

Zhu Alexander Cao, Acton, MA (US);

Assignees:

Novartis AG, Basel, CH;

Amgen Inc., Thousand Oaks, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 31/4184 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); C07K 16/2863 (2013.01); A61K 31/4184 (2013.01); A61K 2039/545 (2013.01);
Abstract

The present invention relates to a pharmaceutical combination comprising a MEK inhibitor compound 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxyethyoxy)-amide or a pharmaceutically acceptable salt thereof and the IGF1R inhibitor ANTIBODY A, a pharmaceutical composition comprising such combination, methods for treating cancer comprising administration of a therapeutically effective amount of such combination to a subject in need thereof, and uses of such combination for the treatment of cancer.


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