The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2015
Filed:
Jun. 26, 2009
Kazunori Kataoka, Tokyo, JP;
Sachiko Kaida, Osaka, JP;
Horacio Cabral, Tokyo, JP;
Michiaki Kumagai, Saitama, JP;
Masaki Sekino, Tokyo, JP;
Kazunori Kataoka, Tokyo, JP;
Sachiko Kaida, Osaka, JP;
Horacio Cabral, Tokyo, JP;
Michiaki Kumagai, Saitama, JP;
Masaki Sekino, Tokyo, JP;
Japan Science and Technology Agency, Kawaguchi-shi, Saitama, JP;
Abstract
The present invention provides a polymer-metal complex composite, which comprises a block copolymer capable of serving as a constituent member of a polymeric micelle and a metal complex having MRI contrast ability, accumulates in a tumor-specific manner, achieves high image contrast even in a small amount, and has reduced side effects and a long retention time in blood. The polymer-metal complex composite of the present invention comprises a block copolymer (A) represented by general formula (a) and a metal complex (B) having MRI contrast ability, wherein the composite comprises a structure in which a carboxyl anion of poly(carbo) in the copolymer (A) is attached to the metal complex (B) via a metal atom (M).