The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 24, 2015

Filed:

Sep. 04, 2009
Applicants:

Eric Ofori Aboagye, Middlesex, GB;

Graham Smith, London, GB;

Quang-de Nguyen, London, GB;

Erik Arstad, London, GB;

Matthias Eberhard Glaser, London, GB;

Inventors:

Eric Ofori Aboagye, Middlesex, GB;

Graham Smith, London, GB;

Quang-De Nguyen, London, GB;

Erik Arstad, London, GB;

Matthias Eberhard Glaser, London, GB;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); A61K 51/00 (2006.01); A61M 36/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01);
Abstract

Isatin 5-sulfonamide derivatives, pharmaceutical compositions comprising the derivatives, their use as molecular imaging agents, their use for the diagnosis or treatment of diseases or disorders associated with dysregulation of apoptosis, methods for synthesizing the derivatives, methods for the molecular imaging of caspase activity and apoptosis, and methods of assessing the therapeutic effect of a test substance on caspase activity are disclosed.


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