The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2015
Filed:
Jul. 02, 2010
Silvio Aime, Carignano, IT;
Valentina Mainero, Ivrea, IT;
Simonetta Chirich Geninatti, Turin, IT;
Claudia Cabella, Pecco, IT;
Silvio Aime, Carignano, IT;
Valentina Mainero, Ivrea, IT;
Simonetta Chirich Geninatti, Turin, IT;
Claudia Cabella, Pecco, IT;
Bracco Imaging S.p.A., Milan, IT;
Abstract
The invention provides MRI detectable species of formula (I)D-S-N  (I)wherein These compounds are useful for internalizing into tumor cells an amount of the MRI detectable moiety that is distinguishably higher than the amount internalized in normal healthy cells thus allowing the diagnosis of tumors. The internalization of the MRI detectable moiety involves the nutrients or pseudo-nutrients transporting system. Preferred compounds of formula (I) are those wherein D is the chelated complex of a paramagnetic metal ion.