The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2015

Filed:

Apr. 01, 2010
Applicants:

Jeffrey Gildersleeve, Frederick, MD (US);

Zhitao LI, Vestal, NY (US);

Qian LI, Timonium, MD (US);

Miriam Anver, Rectortown, VA (US);

Donna O. Butcher, Kearneysville, WV (US);

Inventors:

Jeffrey Gildersleeve, Frederick, MD (US);

Zhitao Li, Vestal, NY (US);

Qian Li, Timonium, MD (US);

Miriam Anver, Rectortown, VA (US);

Donna O. Butcher, Kearneysville, WV (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/30 (2006.01); A61K 51/10 (2006.01); G01N 33/534 (2006.01);
U.S. Cl.
CPC ...
A61K 51/1045 (2013.01); C07K 16/00 (2013.01); C07K 16/30 (2013.01); C07K 16/3092 (2013.01); G01N 33/534 (2013.01); G01N 2400/02 (2013.01);
Abstract

Monoclonal antibodies to carbohydrate antigens containing a terminal GalNAcα1-3Gal are provided. The antibodies of the present invention are found to specifically recognize GalNAcα1-3Gal with little cross-reactivity to other structurally similar antigens such as GalNAcα1-6Gal, blood group A, Forssman antigen and the Tn antigen on both solution assays and human tissue. Compositions comprising the monoclonal antibodies, as well as methods of diagnosis, treatment and prognostication are also provided.


Find Patent Forward Citations

Gildersleeve, Jeffrey. (2015). Antibodies that bind galnac1-3gal, pharmaceutical compositions and methods of using same (U.S. Patent No. 8957188). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8957188

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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