The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2015
Filed:
Feb. 24, 2012
Applicants:
Donald W. Kufe, Wellesley, MA (US);
Surender Kharbanda, Natick, MA (US);
Inventors:
Donald W. Kufe, Wellesley, MA (US);
Surender Kharbanda, Natick, MA (US);
Assignees:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Genus Oncology, LLC, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/03 (2006.01); A61K 38/08 (2006.01); A61K 38/10 (2006.01); C07K 7/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); A61K 38/17 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1735 (2013.01); C07K 7/06 (2013.01); C07K 14/4727 (2013.01);
Abstract
Peptides from the MUC1 cytoplasmic domain and methods of use therefor are described. These peptides can inhibit MUC1 oligomerization, thereby preventing tumor cell growth, inducing tumor cell apoptosis and necrosis of tumor tissue in vivo.