The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2015
Filed:
Apr. 18, 2008
Raymond Dwek, Oxford, GB;
Wanda Buzgariu, Bucharest, RO;
Anca Hirtopeanu, Bucharest, RO;
Robert Moriarty, Chicago, IL (US);
Gabriela Negroiu, Bucharest, RO;
Norica Nichita, Bucharest, RO;
Livia Zdrentu, Bucharest, RO;
Nicole Zitzmann, Oxford, GB;
Raymond Dwek, Oxford, GB;
Wanda Buzgariu, Bucharest, RO;
Anca Hirtopeanu, Bucharest, RO;
Robert Moriarty, Chicago, IL (US);
Gabriela Negroiu, Bucharest, RO;
Norica Nichita, Bucharest, RO;
Livia Zdrentu, Bucharest, RO;
Nicole Zitzmann, Oxford, GB;
Abstract
A proliferation of cells can be reduced by contacting the cells with a compound having formula (I) where R and R' are each alkyl groups, R″ is hydrogen or an alkyl group and X, Xand Xare each independently selected from the group consisting of hydrogen, benzyl, t-butyldimethylsiloxy radical and triphenylmethyl. Accordingly, compounds of formula (I) can be used for treatment of tumors including melanoma. Also a secretion of a matrix metalloproteinase (MMP) enzyme by cells can be reduced by contacting the cells with the compound having formula (I). Accordingly, compounds of formula (I) can be used for treatment physiological conditions associated with an elevated MMP level, such as tumors.