The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2015
Filed:
Jul. 23, 2010
Amos B. Smith, Iii, Merion, PA (US);
Zhuqing Liu, Edison, NJ (US);
Anne-marie L. Hogan, Dublin, IE;
Doralyn S. Dalisay, San Diego, CA (US);
Tadeusz F. Molinski, La Jolla, CA (US);
Amos B. Smith, III, Merion, PA (US);
Zhuqing Liu, Edison, NJ (US);
Anne-Marie L. Hogan, Dublin, IE;
Doralyn S. Dalisay, San Diego, CA (US);
Tadeusz F. Molinski, La Jolla, CA (US);
The Trustees Of The University Of Pennsylvania, Philadelphia, PA (US);
The Regents Of The University Of California, Oakland, CA (US);
Abstract
The present invention is directed to hemi phorboxazole A: and its stereoisomers, as well as derivatives of hemi phorboxazole A of formula I: wherein ring A is aryl or a 5- or 6-membered heteroaryl optionally substituted with one or more of halogen, —OH, or —Calkyl; and R is —CN, a 5- or 6-membered heteroaryl, or halogen; and the pharmaceutically acceptable salt forms thereof, in addition to methods of using these compounds.