The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2015
Filed:
Nov. 15, 2011
Applicants:
Martial Ruat, Orsay, FR;
Helene Faure, Gif-sur-Yvette, FR;
Tatiana Gorojankina, Gif sur Yvette, FR;
Inventors:
Assignee:
Centre National de la Recherche Scientifique, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/04 (2006.01); G01N 33/68 (2006.01); G01N 33/566 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/68 (2013.01); G01N 33/566 (2013.01); G01N 33/5008 (2013.01); G01N 33/574 (2013.01); G01N 2333/726 (2013.01); G01N 2500/04 (2013.01);
Abstract
The present invention relates to the use of quinolinone derivatives of general formula (I), ligands of the Smo receptor or of related receptors which target a binding site of the receptor which is different from the known ligand binding sites, as research tools for identifying modulators of the Smo receptor or of related receptors, characterizing the Hedgehog signalling pathway and diagnosis; the invention also relates to kits containing said derivatives of general formula (I).