The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2015

Filed:

May. 04, 2010
Applicants:

Aihua Zhang, Jiangsu, CN;

Shengtao Yuan, Jiangsu, CN;

Guang Cheng, Jiangsu, CN;

Yipeng Shen, Jiangsu, CN;

Ancheng Ji, Jiangsu, CN;

Inventors:

Aihua Zhang, Jiangsu, CN;

Shengtao Yuan, Jiangsu, CN;

Guang Cheng, Jiangsu, CN;

Yipeng Shen, Jiangsu, CN;

Ancheng Ji, Jiangsu, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/42 (2006.01); A61K 31/44 (2006.01); A01N 43/54 (2006.01); A61K 31/517 (2006.01); A61K 31/47 (2006.01); C07D 239/72 (2006.01); C07D 217/22 (2006.01); C07D 207/00 (2006.01); C07D 207/36 (2006.01); C07D 215/22 (2006.01); C07D 215/48 (2006.01); C07D 217/24 (2006.01); C07D 217/26 (2006.01); C07D 239/52 (2006.01); C07D 239/88 (2006.01); C07D 239/90 (2006.01);
U.S. Cl.
CPC ...
C07D 207/36 (2013.01); C07D 215/22 (2013.01); C07D 215/48 (2013.01); C07D 217/24 (2013.01); C07D 217/26 (2013.01); C07D 239/52 (2013.01); C07D 239/88 (2013.01); C07D 239/90 (2013.01);
Abstract

This present invention discloses a heterocyclic substituted acardite derivate and application thereof, namely compounds in the general formula (1) or the general formula (2) or pharmaceutically acceptable salts thereof, wherein A is monosubstituted or polysubstituted quinoline, isoquinoline, quinazoline, pyrrole or pyrimidine, and the substituent is halogen, Calkyl, Chaloalkyl, Calkoxy, Chaloalkoxy, Calkylamino, Chaloalkylamino, amino or nitryl; Ris Calkyl; Ris one or more selected from hydrogen, halogen, alkyl, alkoxy, haloalkyl or haloalkoxy; and Ris one or more selected from hydrogen, halogen, alkyl, alkoxy, haloalkyl or haloalkoxy. The compound of the present invention and the pharmaceutically acceptable salt thereof can be used for treating tumor or leukemia.


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