The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2015

Filed:

May. 05, 2008
Applicants:

Richard Glickman, Sidney, CA;

Michael R. Hayden, Vancouver, CA;

Noel Hall, Victoria, CA;

Inventors:

Richard Glickman, Sidney, CA;

Michael R. Hayden, Vancouver, CA;

Noel Hall, Victoria, CA;

Assignees:

Aspreva Pharmaceuticals S.A., Neuchatel, CH;

Aspreva Pharmaceuticals Corp., Victoria, British Columbia, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A61K 31/365 (2006.01); A61K 31/343 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/365 (2013.01); A61K 31/343 (2013.01); A61K 31/5377 (2013.01);
Abstract

The disclosure provides methods and compositions for treating a vascular, autoimmune, and/or inflammatory disease, or a condition associated therewith, with a dose of an inosine monophosphate dehydrogenase (IMPDH) inhibitor effective to treat the vascular, autoimmune and/or inflammatory disease, or associated condition but that does not produce immunosuppression sufficient to reduce the risk of allograft rejection. These lower doses of the immunosuppressant avoid the adverse consequences of severe immunosuppression while providing effective treatment of the vascular, autoimmune and/or inflammatory disease.


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