The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2015
Filed:
Feb. 08, 2011
Applicants:
C. Frank Bennett, Carlsbad, CA (US);
Susan M. Freier, San Diego, CA (US);
Sarah Greenlee, San Diego, CA (US);
Eric E. Swayze, Encinitas, CA (US);
Inventors:
C. Frank Bennett, Carlsbad, CA (US);
Susan M. Freier, San Diego, CA (US);
Sarah Greenlee, San Diego, CA (US);
Eric E. Swayze, Encinitas, CA (US);
Assignee:
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12Q 1/68 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 2310/11 (2013.01); C12N 2310/315 (2013.01); C12N 2310/3231 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/341 (2013.01); C12N 2310/346 (2013.01); C12N 2320/34 (2013.01);
Abstract
Disclosed herein are antisense compounds and methods for selectively of reducing expression of an allelic variant of a gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate diseases, including neurodegenerative, such as Huntington's Disease (HD).