The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2015
Filed:
Nov. 14, 2011
Amy Chuong, Cambridge, MA (US);
Nathan Klapoetke, Cambridge, MA (US);
Brian Yichiun Chow, Cambridge, MA (US);
Edward Boyden, Chestnut Hill, MA (US);
Xue Han, Chestnut Hill, MA (US);
Amy Chuong, Cambridge, MA (US);
Nathan Klapoetke, Cambridge, MA (US);
Brian Yichiun Chow, Cambridge, MA (US);
Edward Boyden, Chestnut Hill, MA (US);
Xue Han, Chestnut Hill, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
The invention, in some aspects, relates to compositions and methods for altering cell activity and function. The invention also relates, in part, to the use of light-activated ion pumps (LAIPs) such as a light-activated ion pump polypeptide that when expressed in an excitable cell and contacted with a red light silences the excitable cell, wherein the polypeptide sequence of the light-activated ion pump comprises a wild-type or modifiedorhalorhodopsin polypeptide sequence.