The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2015

Filed:

Mar. 21, 2012
Applicants:

Steven Gareth Griffiths, Moncton, CA;

Scott Edwin Lewis, Westminster, MA (US);

Inventors:

Steven Gareth Griffiths, Moncton, CA;

Scott Edwin Lewis, Westminster, MA (US);

Assignees:

Atlantic Cancer Research Institute, Moncton, New Brunswick, CA;

New England Peptide, Inc., Gardner, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/567 (2006.01); A61K 38/16 (2006.01); C07H 21/04 (2006.01); C12N 15/00 (2006.01); A61K 38/00 (2006.01); A61K 38/04 (2006.01); C07K 14/435 (2006.01); A61K 39/00 (2006.01); C07K 14/34 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/00 (2006.01); C07K 7/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/435 (2013.01); A61K 39/0011 (2013.01); C07K 14/34 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 14/001 (2013.01); C07K 7/00 (2013.01); A61K 2039/6043 (2013.01); C07K 2319/35 (2013.01); C07K 2319/70 (2013.01); G01N 2333/34 (2013.01); G01N 2333/47 (2013.01); G01N 2333/936 (2013.01);
Abstract

The present application is directed to a peptides comprising an a-helix forming-amino acid sequence that binds a heat shock protein. Also included is a polypeptide comprising (a) a first peptide portion that comprises an α-helix-forming amino acid sequence that binds a heat shock protein; and (b) at least one second peptide portion comprising an antigenic amino acid sequence and/or an a-helix-stabilizing amino acid sequence that increases the interaction of the first peptide portion with the heat shock protein. The present application also includes compositions comprising the peptides and/or polypeptides of present application and uses of the peptides and/or polypeptides of the present application for fractionating substances relevant for discovery, research or clinical analysis from a biological sample and as therapeutics.


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