The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2015

Filed:

Dec. 27, 2011
Applicants:

Tetsuro Takamatsu, Kyoto, JP;

Ping Dai, Kyoto, JP;

Inventors:

Tetsuro Takamatsu, Kyoto, JP;

Ping Dai, Kyoto, JP;

Assignee:

LSIP, LLC, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/02 (2006.01); C12N 5/074 (2010.01); C12N 5/0735 (2010.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C12N 2501/605 (2013.01); C12N 2501/603 (2013.01); C12N 2501/10 (2013.01); C12N 2506/45 (2013.01); C12N 2501/604 (2013.01); C12N 2501/999 (2013.01); C12N 2501/608 (2013.01); C12N 5/0606 (2013.01); C12N 2501/606 (2013.01); C12N 2501/60 (2013.01); C12N 2501/602 (2013.01); C12N 5/0678 (2013.01); C12N 2506/1307 (2013.01); C12N 2500/99 (2013.01); C12N 2501/19 (2013.01); C12N 2310/14 (2013.01); C12N 2501/15 (2013.01); C12N 2501/998 (2013.01); C12N 2506/1315 (2013.01);
Abstract

The present invention provides a method for producing iPS cells, comprising reacting cells with at least one connexin inhibitor and at least one TGFβ signaling inhibitor; iPS cells comprising at least one connexin inhibitor; an iPS cell inducer comprising at least one inhibitor selected from the group consisting of connexin inhibitors and TGFβ signaling inhibitors; a medium for inducing iPS cells, comprising at least one inhibitor selected from the group consisting of connexin inhibitors and TGFβ signaling inhibitors; and a kit for inducing iPS cells, comprising at least one inhibitor selected from the group consisting of connexin inhibitors and TGFβ signaling inhibitors.


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