The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2015
Filed:
Oct. 23, 2012
Medical Diagnostic Laboratories, Llc, Hamilton, NJ (US);
Jason Trama, Burlington, NJ (US);
Eli Mordechai, Robbinsville, NJ (US);
Martin E. Adelson, East Windsor, NJ (US);
Medical Diagnostics Laboratories, LLC, Hamilton, NJ (US);
Abstract
Disclosed are methods and compositions for conducting assays utilizing real-time polymerase chain reactions ('PCRs') in detection of serotypes L I, L II, and L III, but not stereotype B, of, capable of causing lymphogranuloma venereum ('LGV'). These assays take advantage of a deletion occurring in the cytotoxin gene locus specific to the L I, L II, and L III serotypes. Each assay employs a first primer having a nucleotide sequence flanking one side of the deletion point and a second primer having a nucleotide sequence flanking the other side of the deletion point, wherein the first primer and the second primer are capable of hybridizing respectively to the plus strand and the minus strand of the genome ofduring PCR. Synthesis during PCR of a sequence-specific amplicon containing this deletion point indicates that the sample contains nucleic acid specific to an LGV-causing serotype of