The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2015

Filed:

Aug. 15, 2011
Applicants:

Francis C. Szoka, Jr., San Francisco, CA (US);

Colin Walsh, Belmont, CA (US);

Vincent Venditto, San Francisco, CA (US);

Juliane Nguyen, San Francisco, CA (US);

Emily Perttu, San Francisco, CA (US);

Inventors:

Francis C. Szoka, Jr., San Francisco, CA (US);

Colin Walsh, Belmont, CA (US);

Vincent Venditto, San Francisco, CA (US);

Juliane Nguyen, San Francisco, CA (US);

Emily Perttu, San Francisco, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 229/00 (2006.01); C07C 229/12 (2006.01); A61K 9/127 (2006.01); C07C 279/14 (2006.01); C07C 309/14 (2006.01); C07F 9/09 (2006.01); C07F 9/54 (2006.01); C07F 9/6509 (2006.01); C07J 9/00 (2006.01); C40B 40/04 (2006.01); A61K 47/18 (2006.01); A61K 47/28 (2006.01); C07J 41/00 (2006.01);
U.S. Cl.
CPC ...
C07C 229/12 (2013.01); A61K 9/1272 (2013.01); C07C 279/14 (2013.01); C07C 309/14 (2013.01); C07F 9/091 (2013.01); C07F 9/54 (2013.01); C07F 9/650958 (2013.01); C07J 9/00 (2013.01); C40B 40/04 (2013.01); A61K 47/186 (2013.01); A61K 47/28 (2013.01); C07J 41/0055 (2013.01);
Abstract

In various embodiments, the present invention provides zwitterionic lipids, encapsulants incorporating these zwitterionic lipids and such encapsulants encapsulating one or more bioactive agent. An exemplary bioactive agent is a nucleic acid. Also provided are pharmaceutical formulations of the encapsulants and methods of using such formulations to deliver a bioactive agent to a subject in treating or diagnosing disease in that subject.


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