The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2015
Filed:
Jan. 21, 2011
Luc Berghman, College Station, TX (US);
Walter Bottje, Fayetteville, AR (US);
Billy Hargis, Fayetteville, AR (US);
Sherryll Layton, Rogers, AR (US);
Luc Berghman, College Station, TX (US);
Walter Bottje, Fayetteville, AR (US);
Billy Hargis, Fayetteville, AR (US);
Sherryll Layton, Rogers, AR (US);
The Texas A&M University System, College Station, TX (US);
The Board of Trustees of the University of Arkansas, Little Rock, AR (US);
Abstract
Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a pharmaceutically acceptable carrier, suitably a carrier for oral or nasal administration. Also provided are methods of enhancing immune responses, in particular antibody immune response and suitably an IgA response, by administering the vaccine vectors or compositions disclosed herein to a subject.