The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2015
Filed:
Jun. 01, 2007
Gursharan S. Chhatwal, Denkte, DE;
Patric D. Nitsche-schmitz, Braunschweig, DE;
Katrin Dinkla, Braunschweig, DE;
Vanessa Barroso, Essex, GB;
Gursharan S. Chhatwal, Denkte, DE;
Patric D. Nitsche-Schmitz, Braunschweig, DE;
Katrin Dinkla, Braunschweig, DE;
Vanessa Barroso, Essex, GB;
Helmholtz-Zentrum für Infektionsforschung GmbH, Braunschweig, DE;
Abstract
The present invention relates to a streptococcal octapeptide AXYLXXLN, and preferably to the octapeptide AXYLZZLN, designated as peptide associated with rheumatic fever (PARF) that, through its interaction with human collagen, plays a crucial role in the pathogenesis of rheumatic fever. PARF therefore represents a marker for rheumatic fever associated strains and provides a target for therapies, and in particular preventive therapies.