The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2015

Filed:

Feb. 27, 2009
Applicants:

Joel A. Virkler, Remington, IN (US);

Lal Ninan, Santa Rosa, CA (US);

Inventors:

Joel A. Virkler, Remington, IN (US);

Lal Ninan, Santa Rosa, CA (US);

Assignee:

Cook Biotech Incorporated, West Lafayette, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 29/00 (2006.01); A61L 31/16 (2006.01); A61L 31/10 (2006.01);
U.S. Cl.
CPC ...
A61L 31/16 (2013.01); A61L 31/10 (2013.01); A61L 2300/236 (2013.01); A61L 2300/252 (2013.01); A61L 2300/414 (2013.01); A61L 2300/45 (2013.01); A61L 2430/36 (2013.01);
Abstract

Described are embolization devices having unique bioactive coatings, as well as methods for their manufacture and use. An illustrative embolization device of the invention comprises an embolic body and a coating material comprising biotropic extracellular matrix material immobilized on a surface of the embolic body. The biotropic extracellular matrix material comprises a network of self-assembled collagen fibrils, and comprises at least one bioactive agent retained in the extracellular matrix material, wherein the bioactive agent is selected from the group consisting of a proteoglycan, a growth factor, a glycoprotein, and a glycosaminoglycan. In certain forms, such an extracellular matrix material comprises a remodelable, angiogenic extracellular matrix material, for example, a submucosa material such as but not limited to porcine small intestinal submucosa.


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