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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8952207 B1

PDFFull Text
Date of Patent:
Feb. 10, 2015

Filed:

Sep. 10, 2008

Copper-catalyzed c—h bond arylation

Applicants:

Olafs Daugulis, Houston, TX (US);

Hien-quang DO, Houston, TX (US);

Inventors:

Olafs Daugulis, Houston, TX (US);

Hien-Quang Do, Houston, TX (US);

Assignee:

The University of Houston System, Houston, TX (US);

Attorney:

Robert W Strozier

Primary Examiner:

Clinton Brooks

Int. Cl.
CPC ...
C07C 22/00 (2006.01); C07C 25/13 (2006.01); C07F 9/02 (2006.01); C07D 333/00 (2006.01); C07D 409/02 (2006.01); C07B 37/04 (2006.01); C07C 17/269 (2006.01); C07C 41/30 (2006.01); C07C 45/68 (2006.01); C07C 253/30 (2006.01); C07D 213/06 (2006.01); C07D 213/89 (2006.01); C07D 215/04 (2006.01); C07D 237/08 (2006.01); C07D 239/26 (2006.01); C07D 239/74 (2006.01); C07D 249/08 (2006.01); C07D 263/32 (2006.01); C07D 263/57 (2006.01); C07D 277/22 (2006.01); C07D 277/66 (2006.01); C07D 307/79 (2006.01); C07D 333/06 (2006.01); C07D 333/12 (2006.01); C07D 333/54 (2006.01); C07D 413/04 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07B 37/04 (2013.01); C07C 17/269 (2013.01); C07C 41/30 (2013.01); C07C 45/68 (2013.01); C07C 253/30 (2013.01); C07D 213/06 (2013.01); C07D 213/89 (2013.01); C07D 215/04 (2013.01); C07D 237/08 (2013.01); C07D 239/26 (2013.01); C07D 239/74 (2013.01); C07D 249/08 (2013.01); C07D 263/32 (2013.01); C07D 263/57 (2013.01); C07D 277/22 (2013.01); C07D 277/66 (2013.01); C07D 307/79 (2013.01); C07D 333/06 (2013.01); C07D 333/12 (2013.01); C07D 333/54 (2013.01); C07D 413/04 (2013.01); C07D 471/04 (2013.01); C07C 2101/14 (2013.01);
Abstract

The present invention is a one-step method for efficiently converting carbon-hydrogen bonds into carbon-carbon bonds using a combination of aryl halides, a substrate, and a copper salt as catalyst. This method allows faster introduction of complex molecular entities, a process that would otherwise require many more steps. This invention is particularly relevant for the organic synthesis of complex molecules such as, but not limited to, pharmacophores and explosives.

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Daugulis, Olafs. (2015). Copper-catalyzed c—h bond arylation (U.S. Patent No. 8952207). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8952207

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