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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8952180 B1

PDFFull Text
Date of Patent:
Feb. 10, 2015

Filed:

Sep. 25, 2012

Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors

Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Lynn Abell, Washington Crossing, PA (US);

Leonard Adam, Doylestown, PA (US);

Cullen L. Cavallaro, Robbinsville, NJ (US);

Heather Finlay, Skillman, NJ (US);

Todd J. Friends, Bordentown, NJ (US);

Jon J. Hangeland, Morrisville, PA (US);

Ji Jiang, West Windsor, NJ (US);

R. Michael Lawrence, Yardley, PA (US);

John Lloyd, Yardley, PA (US);

Zulan Pi, Pennington, NJ (US);

George O. Tora, Langhorne, PA (US);

Jennifer X. Qiao, Princeton, NJ (US);

Carol Hui Hu, New Hope, PA (US);

Tammy C. Wang, Lawrenceville, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:

Jing G. Sun

Primary Examiner:

Heidi Reese

Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/40 (2006.01); C07D 221/02 (2006.01); C07D 205/00 (2006.01); C07D 207/38 (2006.01); C07D 403/12 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 405/06 (2006.01); C07D 405/12 (2006.01); C07D 417/04 (2006.01); C07D 417/06 (2006.01); C07D 471/04 (2006.01); C07D 207/28 (2006.01); C07D 417/12 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 207/38 (2013.01); C07D 403/12 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01); C07D 417/04 (2013.01); C07D 417/06 (2013.01); C07D 471/04 (2013.01); C07D 207/28 (2013.01); C07D 417/12 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention provides compounds of Formula (I) or Formula (III): [INSERT CHEMICAL STRUCTURE HERE] (I) [INSERT CHEMICAL STRUCTURE HERE] (III) as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used as medicaments.

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