IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8952169 B1

PDFFull Text
Date of Patent:
Feb. 10, 2015

Filed:

May. 21, 2013

N-substituted benzamides and methods of use thereof

Applicants:

Genentech, Inc., South San Francisco, CA (US);

Xenon Pharmaceuticals Inc., Burnaby, CA;

Inventors:

Jean-Christophe Andrez, Burnaby, CA;

Sultan Chowdhury, Burnaby, CA;

Shannon Marie Decker, Burnaby, CA;

Christoph Martin Dehnhardt, Burnaby, CA;

Thilo Focken, Burnaby, CA;

Michael Edward Grimwood, Burnaby, CA;

Ivan William Hemeon, Burnaby, CA;

Qi Jia, Burnaby, CA;

Jun Li, South San Francisco, CA (US);

Daniel F. Ortwine, South San Francisco, CA (US);

Brian Safina, South San Francisco, CA (US);

Tao Sheng, Burnaby, CA;

Shaoyi Sun, Burnaby, CA;

Daniel P. Sutherlin, South San Francisco, CA (US);

Michael Scott Wilson, Burnaby, CA;

Alla Yurevna Zenova, Burnaby, CA;

Assignees:

Xenon Pharmaceuticals Inc., Burnaby, CA;

Genentech, Inc., South San Francisco, CA (US);

Attorney:

Viksnins Harris & Padys PLLP

Primary Examiner:

John Mabry

Assistant Examiner:

Daniel Carcanague

Int. Cl.
CPC ...
C07C 311/51 (2006.01); C07D 403/12 (2006.01); C07D 213/82 (2006.01); C07D 213/64 (2006.01); C07D 205/04 (2006.01); C07D 311/58 (2006.01); A61K 31/445 (2006.01); A61K 31/44 (2006.01); A61K 31/18 (2006.01); C07D 265/30 (2006.01); C07D 233/84 (2006.01); C07D 257/04 (2006.01); C07C 307/06 (2006.01); C07D 295/26 (2006.01); C07D 207/48 (2006.01); C07D 311/70 (2006.01); C07D 413/12 (2006.01); C07D 451/02 (2006.01); C07D 307/12 (2006.01); C07D 309/08 (2006.01); C07D 311/72 (2006.01); C07D 405/12 (2006.01); C07D 491/107 (2006.01); C07D 211/22 (2006.01); C07D 295/192 (2006.01); C07D 211/96 (2006.01); C07D 307/18 (2006.01);
U.S. Cl.
CPC ...
C07D 311/51 (2013.01); C07D 403/12 (2013.01); C07D 213/82 (2013.01); C07D 213/64 (2013.01); C07D 205/04 (2013.01); C07D 311/58 (2013.01); C07D 265/30 (2013.01); C07D 233/84 (2013.01); C07D 257/04 (2013.01); C07C 307/06 (2013.01); C07D 295/26 (2013.01); C07D 207/48 (2013.01); C07D 311/70 (2013.01); C07D 413/12 (2013.01); C07D 451/02 (2013.01); C07D 307/12 (2013.01); C07D 309/08 (2013.01); C07D 311/72 (2013.01); C07D 405/12 (2013.01); C07D 491/107 (2013.01); C07D 211/22 (2013.01); C07D 295/192 (2013.01); C07D 211/96 (2013.01); C07D 307/18 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01); C07C 2101/18 (2013.01); C07C 2102/10 (2013.01); C07C 2102/42 (2013.01); C07C 2102/44 (2013.01); C07C 2103/74 (2013.01); C07B 2200/05 (2013.01); C07C 2101/02 (2013.01); C07C 2101/04 (2013.01); C07C 2101/16 (2013.01); C07C 2102/18 (2013.01); C07C 2102/20 (2013.01); C07C 2102/50 (2013.01); C07C 2103/68 (2013.01);
Abstract

The invention provides novel compounds having the general formula: and pharmaceutically acceptable salts thereof, wherein the variables R, subscript n, ring A, X, L, subscript m, X, B, R, R, R, R, Rand Rhave the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

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