The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 2015

Filed:

Jul. 29, 2010
Applicants:

Hirokazu Kobayashi, Yokohama, JP;

Nobuo Kubota, Yokohama, JP;

Inventors:

Hirokazu Kobayashi, Yokohama, JP;

Nobuo Kubota, Yokohama, JP;

Assignees:

Pola Pharma Inc., Shinagawa-ku, Tokyo, JP;

Nihon Nohyaku Co., Ltd., Chuo-ku, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/10 (2006.01); A01N 25/00 (2006.01); A61K 31/4178 (2006.01); A61K 9/00 (2006.01); A61K 47/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4178 (2013.01); A61K 9/0014 (2013.01); A61K 47/08 (2013.01);
Abstract

A pharmaceutical composition which comprises 1) a compound represented by the following general formula (1) and/or a salt thereof; and 2) a ketone such as methyl ethyl ketone. Preferably, the compound represented by the following general formula (1) is luliconazole, where R═R=a chlorine atom: where Rand Reach independently represents a hydrogen atom or a halogen atom, and at least one of Rand Rrepresents a halogen atom. The present invention provides a preparation excellent in solubilization stability for a compound represented by the general formula (1) and/or a salt thereof in low-temperature or high-temperature storage.


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