The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2015
Filed:
Nov. 14, 2012
Applicants:
The Hospital for Sick Children, Toronto, CA;
Mcmaster University, Hamilton, CA;
Inventors:
Don J Mahuran, Toronto, CA;
Michael B Tropak, Toronto, CA;
Justin D Buttner, Rosehill, AU;
Jan E Blanchard, St. Catherines, CA;
Eric D Brown, Oakville, CA;
Assignees:
The Hospital for Sick Children, Toronto, CA;
McMaster University, Toronto, CA;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/58 (2006.01); A61K 31/56 (2006.01); A61K 31/397 (2006.01); A61K 31/54 (2006.01); A61K 31/136 (2006.01); A61K 31/137 (2006.01); A61K 31/138 (2006.01); A61K 31/495 (2006.01); A61K 31/496 (2006.01); A61K 31/5415 (2006.01); A61K 31/553 (2006.01); A61K 45/06 (2006.01); A61K 31/167 (2006.01); A61K 31/235 (2006.01);
U.S. Cl.
CPC ...
A61K 31/136 (2013.01); A61K 31/137 (2013.01); A61K 31/138 (2013.01); A61K 31/495 (2013.01); A61K 31/496 (2013.01); A61K 31/5415 (2013.01); A61K 31/553 (2013.01); A61K 31/56 (2013.01); A61K 31/58 (2013.01); A61K 45/06 (2013.01); A61K 31/167 (2013.01); A61K 31/235 (2013.01);
Abstract
Therapeutic compositions and methods for treatment of late-onset Gaucher disease are described herein. The compositions comprise compounds having activity as pharmacological chaperones for mutant forms of the beta-glucocerebrosidase. Methods of treatment involve providing therapeutically effective amounts of such compositions to subjects in need thereof.