The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2015
Filed:
Mar. 29, 2010
Yusuke Mizukami, Hokkaido, JP;
Junpei Sasajima, Hokkaido, JP;
Yoshiaki Sugiyama, Hokkaido, JP;
Kazuya Sato, Hokkaido, JP;
Yutaka Kohgo, Hokkaido, JP;
Yusuke Mizukami, Hokkaido, JP;
Junpei Sasajima, Hokkaido, JP;
Yoshiaki Sugiyama, Hokkaido, JP;
Kazuya Sato, Hokkaido, JP;
Yutaka Kohgo, Hokkaido, JP;
National University Corporation Asahikawa Medical University, Hokkaido, JP;
Abstract
The present invention relates to a method of safely and simply inducing differentiation of mononuclear cells into cells that promote neovascular stabilization and maturation, and lead to recovering from ischemia or tissue repair. The cells according to the present invention are obtained by inducing differentiation of a mononuclear cell by culturing the mononuclear cell in a medium (particularly a serum-free medium) containing one or more selected from vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), thrombopoietin (TPO), granulocyte-colony stimulating factor (G-CSF) and FMS-like tyrosine kinase 3 ligand (FLT3L), and collecting a cell population expressing CD11b.