The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2015
Filed:
Nov. 28, 2008
Bernhard Hauer, Fussgönheim, DE;
Nina Schneider, Offenburg, DE;
Krzysztof Okrasa, Manchester, GB;
Jason Micklefield, Stockport, GB;
David Leys, Todmorden, GB;
Colin Levy, Rawtenstall, GB;
Bernhard Hauer, Fussgönheim, DE;
Nina Schneider, Offenburg, DE;
Krzysztof Okrasa, Manchester, GB;
Jason Micklefield, Stockport, GB;
David Leys, Todmorden, GB;
Colin Levy, Rawtenstall, GB;
BASF SE, Ludwigshafen, DE;
Abstract
The present invention relates to a method for the enzymatic decarboxylation of malonic acid (propanedioic acid) derivatives catalyzed by enzymes structurally and/or functionally related to arylmalonate decarboxylase (AMDase) as isolated from microorganisms of the genus. The present invention also relates to novel enzymes with a decarboxylase activity, useful for performing the claimed method, mutants thereof, corresponding coding sequences and expression systems, methods of preparing said novel enzymes, and screening methods for obtaining further suitable enzymes also having said decarboxylase activity.