The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2015
Filed:
Apr. 30, 2013
Applicant:
Theravectys, Villejuif, FR;
Inventors:
Cecile Bauche, Paris, FR;
Emeline Sarry, Malakoff, FR;
Assignee:
Theravectys, Villejuif, FR;
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/01 (2006.01); C12N 15/00 (2006.01); A61K 39/00 (2006.01); C12N 15/86 (2006.01); A61K 39/39 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 15/00 (2013.01); A61K 2039/51 (2013.01); A61K 2039/57 (2013.01); C12N 2740/15011 (2013.01); C12N 2740/15041 (2013.01); A61K 39/00 (2013.01); C12N 2740/15034 (2013.01); C12N 2830/008 (2013.01); A61K 39/39 (2013.01);
Abstract
The present invention relates to the insertion of a promoter sequence from an MHC class I gene promoter into a lentiviral vector in order to direct the transcription of a transgene, which preferably encodes an immunogenic polypeptide to be expressed in a mammalian cell host, preferably APC (DCs). The invention encompasses these vectors, methods of making the vectors, and methods of using them, including medicinal uses.