The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 2015

Filed:

Aug. 08, 2008
Applicants:

Bakthan Singaram, Santa Cruz, CA (US);

Ritchie A. Wessling, Watsonville, CA (US);

Inventors:

Bakthan Singaram, Santa Cruz, CA (US);

Ritchie A. Wessling, Watsonville, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 10/00 (2006.01); A61B 8/00 (2006.01); A61B 5/00 (2006.01); A61K 49/00 (2006.01); B82Y 5/00 (2011.01); B82Y 10/00 (2011.01); B82Y 15/00 (2011.01); B82Y 30/00 (2011.01); C07D 213/82 (2006.01); C07F 5/02 (2006.01); C09K 9/02 (2006.01); G01N 33/542 (2006.01); G01N 33/543 (2006.01); G01N 33/58 (2006.01); G01N 33/66 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0019 (2013.01); B82Y 5/00 (2013.01); B82Y 10/00 (2013.01); B82Y 15/00 (2013.01); B82Y 30/00 (2013.01); C07D 213/82 (2013.01); C07F 5/025 (2013.01); C09K 9/02 (2013.01); G01N 33/542 (2013.01); G01N 33/543 (2013.01); G01N 33/582 (2013.01); G01N 33/66 (2013.01); C09K 2211/1007 (2013.01); C09K 2211/1011 (2013.01); C09K 2211/1029 (2013.01);
Abstract

The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.


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