The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 2015

Filed:

Sep. 06, 2006
Applicants:

D. Scott Wilbur, Edmonds, WA (US);

Bengt E. B. Sandberg, Hjärup, SE;

Inventors:

D. Scott Wilbur, Edmonds, WA (US);

Bengt E. B. Sandberg, Hjärup, SE;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); C07D 235/02 (2006.01); C07F 5/00 (2006.01); A61K 31/4188 (2006.01); A61K 31/765 (2006.01); C07D 233/32 (2006.01); C07D 495/04 (2006.01); C07D 519/00 (2006.01); G01N 33/532 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4188 (2013.01); A61K 31/765 (2013.01); C07D 233/32 (2013.01); C07D 495/04 (2013.01); C07D 519/00 (2013.01); G01N 33/532 (2013.01); G01N 33/54353 (2013.01);
Abstract

A reagent for conjugation to a biomolecule, wherein the reagent is a single molecule with at least three functional parts and has schematic structure (I): a) wherein a trifunctional cross-linking moiety is coupled to b) an affinity ligand via a linker 1, said affinity ligand being capable of binding with another molecule having affinity for said ligand, to c) an effector agent, optionally via a linker 2, said effector agent exerting its effect on cells, tissues and/or humorous molecules in vivo or ex vivo, and to d) a biomolecule reactive moiety, optionally via a linker 3, said moiety being capable of forming a bond between the reagent and the biomolecule.


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