The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Sep. 18, 2008
Applicant:

Yingtian Pan, Stony Brook, NY (US);

Inventor:

Yingtian Pan, Stony Brook, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/05 (2006.01); A61B 5/00 (2006.01); G01N 21/47 (2006.01); G02B 3/00 (2006.01); G02B 13/22 (2006.01);
U.S. Cl.
CPC ...
A61B 5/6852 (2013.01); A61B 5/0066 (2013.01); G01N 21/4795 (2013.01); G02B 3/0087 (2013.01); G02B 13/22 (2013.01);
Abstract

In general, in one aspect, the invention features a method that includes using an optical coherence tomography system to acquire a plurality of frames of a sample where each frame includes optical information about the composition of the sample through a section of the sample. The method further includes averaging over two or more of the frames to provide an image of the section of the sample where successive frames of the two or more frames are acquired with a time lapse of 0.05-0.7 seconds. Embodiments of the method may have unique advantages for endoscopic subcellular imaging. For example, they can enable subcellular imaging with low-NA optics (e.g., NA=0.25 or less) while providing morphological imaging of the underlying tissue up to 0.6 mm without focal tracking.


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