The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Nov. 06, 2009
Applicants:

Didier Bouvy, Brussels, BE;

Alain Merschaert, Brussels, BE;

Véronique Pinilla, Brussels, BE;

Joerg Hamann, Köln, DE;

Ralf Kanzler, Leverkussen, DE;

Antoine Thomas, Lille, FR;

Inventors:

Didier Bouvy, Brussels, BE;

Alain Merschaert, Brussels, BE;

Véronique Pinilla, Brussels, BE;

Joerg Hamann, Köln, DE;

Ralf Kanzler, Leverkussen, DE;

Antoine Thomas, Lille, FR;

Assignee:

UCB Pharma GmbH, Monheim, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 231/20 (2006.01); C07C 237/22 (2006.01); C07C 231/18 (2006.01);
U.S. Cl.
CPC ...
C07C 231/20 (2013.01); C07C 231/18 (2013.01); C07C 237/22 (2013.01);
Abstract

The present patent application relates to an alternative process for the preparation of amino derivatives. In particular, the present application relates to an improved process for the manufacture of Lacosamide (LCM), (R)-2-acetamido-N-benzyl-3-methoxypropion-amide, which is useful as an anticonvulsive drug. In a particular aspect, the present invention relates to a process of manufacture of optically enriched (R)-2-acetamido-N-benzyl-3-methoxypropion-amide (I) comprising resolution of 2-acetamido-N-benzyl-3-methoxypropion-amide (II).


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