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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8946439 B1

PDFFull Text
Date of Patent:
Feb. 03, 2015

Filed:

Feb. 27, 2009

Amide compounds, compositions and uses thereof

Applicants:

Zhi-liang Wei, Foster City, CA (US);

Sumithra Gowlugari, Hayward, CA (US);

Carl Kaub, San Diego, CA (US);

Zhan Wang, Palo Alto, CA (US);

Yeyu Cao, Foster City, CA (US);

John Kincaid, Hayward, CA (US);

Inventors:

Zhi-Liang Wei, Foster City, CA (US);

Sumithra Gowlugari, Hayward, CA (US);

Carl Kaub, San Diego, CA (US);

Zhan Wang, Palo Alto, CA (US);

Yeyu Cao, Foster City, CA (US);

John Kincaid, Hayward, CA (US);

Assignee:

Evotec AG, Hamburg, DE;

Attorney:

Klauber & Jackson LLC

Primary Examiner:

Venkataraman Balasubramanian

Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 401/14 (2006.01); A61K 31/166 (2006.01); A61K 31/40 (2006.01); A61K 31/4427 (2006.01); A61K 31/444 (2006.01); A61P 19/02 (2006.01); C07D 213/56 (2006.01); C07D 277/30 (2006.01); C07D 205/04 (2006.01); C07D 317/48 (2006.01); C07D 213/61 (2006.01); C07D 333/54 (2006.01); C07D 231/12 (2006.01); C07D 241/12 (2006.01); C07D 265/36 (2006.01); C07D 239/47 (2006.01); C07D 249/08 (2006.01); C07D 239/26 (2006.01); C07D 471/04 (2006.01); C07D 263/56 (2006.01); C07D 413/04 (2006.01); C07D 231/16 (2006.01); C07D 239/34 (2006.01); C07D 403/12 (2006.01); C07D 489/04 (2006.01); C07D 213/643 (2006.01); C07D 295/104 (2006.01); C07D 417/12 (2006.01); C07D 215/12 (2006.01);
U.S. Cl.
CPC ...
C07D 213/643 (2013.01); C07D 213/56 (2013.01); C07D 277/30 (2013.01); C07D 205/04 (2013.01); C07D 401/12 (2013.01); C07D 317/48 (2013.01); C07D 213/61 (2013.01); C07D 333/54 (2013.01); C07D 231/12 (2013.01); C07D 241/12 (2013.01); C07D 265/36 (2013.01); C07D 239/47 (2013.01); C07D 249/08 (2013.01); C07D 239/26 (2013.01); C07D 471/04 (2013.01); C07D 263/56 (2013.01); C07D 401/14 (2013.01); C07D 413/04 (2013.01); C07D 231/16 (2013.01); C07D 239/34 (2013.01); C07D 403/12 (2013.01); C07D 489/04 (2013.01); C07D 295/104 (2013.01); C07D 417/12 (2013.01); C07D 215/12 (2013.01);
Abstract

Compounds are provided according to formula 1: where A, B, W, X', L, R, R, R, and m′ are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.

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