The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2015
Filed:
Oct. 24, 2011
Barton James Bradbury, Wallingford, CT (US);
Jason Allan Wiles, Hamden, CT (US);
Qiuping Wang, Bethany, CT (US);
Akhiro Hashimoto, Branford, CT (US);
Edlaine Lucien, New Haven, CT (US);
Godwin Clarence Gilroy Pais, Hampden, CT (US);
Milind Deshpande, Madison, CT (US);
Micheal John Pucci, Kensington, CT (US);
Ha Young Kim, Cheshire, CT (US);
Barton James Bradbury, Wallingford, CT (US);
Jason Allan Wiles, Hamden, CT (US);
Qiuping Wang, Bethany, CT (US);
Akhiro Hashimoto, Branford, CT (US);
Edlaine Lucien, New Haven, CT (US);
Godwin Clarence Gilroy Pais, Hampden, CT (US);
Milind Deshpande, Madison, CT (US);
Micheal John Pucci, Kensington, CT (US);
Ha Young Kim, Cheshire, CT (US);
Achillion Pharmaceuticals, Inc., New Haven, CT (US);
Abstract
The invention provides compound and salts of Formula I and II, disclosed herein, which includes compounds of Formula A and Formula B: Such compounds possess useful antimicrobial activity. The variables R, R, R, R, R, and Rshown in Formula A and B are defined herein. Certain compounds of Formula I and Formula II disclosed herein are potent and/or selective inhibitors of bacterial DNA synthesis and bacterial replication. The invention also provides antimicrobial compositions, including pharmaceutical compositions, containing one or more compounds of Formula I or Formula II and one or more carriers, excipients, or diluents. Such compositions may contain a compound of Formula I or Formula II as the only active agent or may contain a combination of a compound of Formula I or Formula II and one or more other active agents. The invention also provides methods for treating microbial infections in animals.