The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2015
Filed:
Dec. 20, 2013
Applicant:
Glaxosmithkline Biologicals S.a., Rixensart, BE;
Inventor:
David A. Johnson, Hamilton, MT (US);
Assignee:
GlaxoSmithKline Biologicals S.A., Rixensart, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/06 (2006.01);
U.S. Cl.
CPC ...
C07D 471/06 (2013.01);
Abstract
The compounds of the subject invention are adjuvant molecules that comprise an imidazoquinoline molecule covalently linked to a phospho- or phosphonolipid group. The compounds of the invention have been shown to be inducers of interferon-a, IL-12 and other immunostimulatory cytokines and possess an improved activity profile in comparison to known cytokine inducers when used as adjuvants for vaccine antigens.