The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Jun. 22, 2012
Applicants:

Robert O. Cook, Hillsborough, NJ (US);

Jian Zhang, Mountain View, CA (US);

Thomas A. Armer, Mountain View, CA (US);

Inventors:

Robert O. Cook, Hillsborough, NJ (US);

Jian Zhang, Mountain View, CA (US);

Thomas A. Armer, Mountain View, CA (US);

Assignee:

Map Pharmaceuticals, Inc., Irvine, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/48 (2006.01); C07D 457/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/48 (2013.01); C07D 457/12 (2013.01);
Abstract

Provided herein are novel neuromodulatory compounds and compositions thereof. In other embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, migraine and Parkinson's disease, using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of agonizing receptors such as, for example, the 5-HTand/or the 5-HTreceptor, without agonizing the 5-HTreceptor using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing or inhibiting activity at receptors such as, for example, the adrenergic alphaand/or the alphareceptors using the compounds and compositions disclosed herein. In other embodiments, provided herein are methods of agonizing dopaminergic Dreceptors and/or antagonizing or inhibiting activity of receptors such as the 5-HTreceptors using the compounds and compositions disclosed herein.


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