The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Oct. 08, 2010
Applicants:

John Woodcraft, Amersham, GB;

L Clare Jones, Amersham, GB;

Alessandra Gaeta, Amersham, GB;

John William Trigg, Amersham, GB;

Alexander Paul Jones, Amersham, GB;

Stuart Plant, Amersham, GB;

Alexander Jackson, Amersham, GB;

Inventors:

John Woodcraft, Amersham, GB;

L Clare Jones, Amersham, GB;

Alessandra Gaeta, Amersham, GB;

John William Trigg, Amersham, GB;

Alexander Paul Jones, Amersham, GB;

Stuart Plant, Amersham, GB;

Alexander Jackson, Amersham, GB;

Assignee:

GE Healthcare Limited, Amersham, Buckinghamshire, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract

The present invention provides a method to obtain radiofluorinated compounds useful for in vivo imaging GABAreceptors. The method of the invention is high-yielding and may conveniently be carried out on an automated synthesizer such as Fastlab™. A further aspect of the invention is a cassette suitable for carrying out the automated method of synthesis of the invention. Novel precursor compounds useful in the method of the invention are also provided, as are a number of novel compounds obtained by the method of the invention.


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