The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Jul. 13, 2010
Applicants:

Tongfei Wu, Jette, BE;

Henricus Jacobus Maria Gijsen, Breda, NL;

Frederik Jan Rita Rombouts, Wilrijk, BE;

François Paul Bischoff, Vosselaar, BE;

Didier Jean-claude Berthelot, Edegem, BE;

Daniel Oehlrich, Malle, BE;

Michel Anna Jozef DE Cleyn, Lille, BE;

Serge Maria Aloysius Pieters, Hulst, NL;

Garrett Berlond Minne, Bissegem, BE;

Adriana Ingrid Velter′, Antwerp, BE;

Sven Franciscus Anna Van Brandt, Lier, BE;

Michel Surkyn, Merksplas, BE;

Assignees:

Janssen Pharmaceuticals, Inc., Titusville, NJ (US);

Cellzome Limited, Brentford, Middlesex, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); C07D 401/14 (2006.01); C07D 233/60 (2006.01); C07D 403/10 (2006.01); C07D 405/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 233/60 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 405/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01);
Abstract

The present invention is concerned with novel substituted triazole and imidazole derivatives of Formula (I) wherein R, R, A, A, A, A, X, and Hethave the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.


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