The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Mar. 01, 2010
Applicants:

Vinayak Govind Gore, Maharashtra, IN;

Vinay Kumar Shukla, Maharashtra, IN;

Shreyas Shrikant Bhandari, Maharashtra, IN;

Suresh Hasbe, Maharashtra, IN;

Inventors:

Vinayak Govind Gore, Maharashtra, IN;

Vinay Kumar Shukla, Maharashtra, IN;

Shreyas Shrikant Bhandari, Maharashtra, IN;

Suresh Hasbe, Maharashtra, IN;

Assignee:

Generics [UK] Limited, Hertfordshire, GB;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 211/88 (2006.01); C07D 209/44 (2006.01); C07D 401/04 (2006.01); A61K 31/454 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01);
Abstract

The present invention relates to improved processes for preparing 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione (I) (lenalidomide) and its intermediate 3-(1-oxo-4-nitro-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione. The present invention further relates to improved processes for preparing lenalidomide crystalline form A, use of said crystalline form A as an active pharmaceutical ingredient or as an intermediate in the preparation of further crystalline or amorphous forms of lenalidomide, compositions comprising lenalidomide crystalline form A and their use in the treatment of disease.


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