The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Jan. 24, 2012
Applicants:

Kuldeep Kumar Roy, Lucknow, IN;

Santoshkumar Tota, Lucknow, IN;

Chandishwar Nath, Lucknow, IN;

Rakesh Shukla, Lucknow, IN;

Anil Kumar Saxena, Lucknow, IN;

Inventors:

Kuldeep Kumar Roy, Lucknow, IN;

Santoshkumar Tota, Lucknow, IN;

Chandishwar Nath, Lucknow, IN;

Rakesh Shukla, Lucknow, IN;

Anil Kumar Saxena, Lucknow, IN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/20 (2006.01); A61K 31/04 (2006.01);
U.S. Cl.
CPC ...
C07D 215/20 (2013.01);
Abstract

The present invention relates to novel substituted 1,2,3,4-tetrahydroquinolin-7-yl carbamates, their preparation, and use as therapeutic agents, particularly in the prevention or treatment of neurodegenerative or Alzheimer's disease, or senile dementia, or memory disturbances, and more particularly to the prevention, treatment and amelioration of Alzheimer's disease with the novel substituted 1,2,3,4-tetrahydroquinolin-7-yl carbamates, which act as inhibitors of central cholinesterase enzymes, particularly acetylcholinesterase (AChE) following the indirect cholinomimetic pathway. The present invention particularly relates to compounds of formula A: Formula A wherein R=alkyl, aryl, substituted aryl; R=H, methyl; R=H, alkyl, alkenyl, alkynyl, aralkyl, substituted aralkyl, aryl, heteroaryl.


Find Patent Forward Citations

Roy, Kuldeep. (2015). Substituted 1, 2, 3, 4-tetrahydroquinolin-7-yl carbamates as acetylcholinesterase inhibitors for treatment of alzheimer's disease (U.S. Patent No. 8946261). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8946261

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