The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Jan. 11, 2011
Applicants:

Jongwon Lim, Lexington, MA (US);

Brandon M. Taoka, Hoboken, NJ (US);

Sandra Lee, Princeton, NJ (US);

Alan Northrup, Reading, MA (US);

Michael D. Altman, Needham, MA (US);

David L. Sloman, Boston, MA (US);

Matthew G. Stanton, Marlton, NJ (US);

Njamkou Noucti, Carrboro, NC (US);

Inventors:

Jongwon Lim, Lexington, MA (US);

Brandon M. Taoka, Hoboken, NJ (US);

Sandra Lee, Princeton, NJ (US);

Alan Northrup, Reading, MA (US);

Michael D. Altman, Needham, MA (US);

David L. Sloman, Boston, MA (US);

Matthew G. Stanton, Marlton, NJ (US);

Njamkou Noucti, Carrboro, NC (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/90 (2006.01); A61K 31/519 (2006.01); C07D 487/00 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract

The invention encompasses pyrazolo[1,5-a]pyrimidine derivatives which selectively inhibit microtubule affinity regulating kinase (MARK) and are therefore useful for the treatment or prevention of Alzheimer's disease. Pharmaceutical compositions and methods of use are also included.


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