The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2015
Filed:
Jul. 28, 2009
Applicants:
Marina Ciomei, Corsico, IT;
Francesco Fiorentini, Milan, IT;
Enrico Pesenti, Parabiago, IT;
Inventors:
Assignee:
Nerviano Medical Sciences S.r.l., Nerviano (MI), IT;
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); A61K 31/4188 (2006.01); A61K 31/519 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/4188 (2013.01); A61K 45/06 (2013.01);
Abstract
The invention provides a low molecular weight ATP-competitive CDK inhibitor able to cross the blood brain barrier for use in the treatment of malignant glioma and, in particular, of glioblastoma. The compound can be administered together with one or more agents selected from the group consisting of cytotoxic or cytostatic agents and ionizing radiation.