The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2015
Filed:
Nov. 12, 2010
Celia Dominguez, Los Angeles, CA (US);
John Wityak, Carlsbad, CA (US);
Michael Prime, Oxfordshire, GB;
Stephen Martin Courtney, Oxfordshire, GB;
Christopher Yarnold, Oxfordshire, GB;
Frederick Brookfield, Oxfordshire, GB;
Richard Marston, Oxfordshire, GB;
Douglas Macdonald, Los Angeles, CA (US);
Celia Dominguez, Los Angeles, CA (US);
John Wityak, Carlsbad, CA (US);
Michael Prime, Oxfordshire, GB;
Stephen Martin Courtney, Oxfordshire, GB;
Christopher Yarnold, Oxfordshire, GB;
Frederick Brookfield, Oxfordshire, GB;
Richard Marston, Oxfordshire, GB;
Douglas Macdonald, Los Angeles, CA (US);
CHDI Foundation, Inc., New York, NY (US);
Abstract
Certain compounds and pharmaceutically acceptable salts are provided herein. Also provided are pharmaceutical compositions comprising at least one compound or pharmaceutically acceptable salt therein and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain disease states responsive to the inhibition of transglutaminase TG2 activity are described. These disease states include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one compound or pharmaceutically acceptable salt thereof as a single active agent or administering at least one compound or pharmaceutically acceptable salt thereof in combination with one or more other therapeutic agents.